PolyA Cleavage Site & 3' UTR Database
Welcome to PACdb Public Release Version 1
[Sept 10, 2008] Our support Email address  is back up after Exchange Server migration.
[Jan 15, 2007] New human data available (assembly 36). Human and mouse BLAST and genomic alignment functionality unavailable, will be updated soon. The data download page will be updated soon as well, for both human and mouse.
PACdb is a database of mRNA three prime (3')
processing sites. These sites are also called
polyadenylation cleavage sites (or PAC sites) because they are the
location that the mRNA is cleaved and a 3' polyadenylate tail is added
for most eukaryotic mRNAs. The location of these sites determines
the length of the 3' untranslated region (3' UTR) of the mRNA transcript.
ESTs (Expressed Sequence Tags) are used to identify putative 3'-processing sites,
and these putative 3'-processing sites can then be used to retrieve 3' UTR length
and sequence. PACdb is also an excellent resource to study
alternative polyadenylation since it catalogs all putative 3'-processing sites
across many organisms.
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